>>>dr. margileth: triple negative breast canceris defined as a breast cancer that is estrogen receptor negative, progesterone receptor negative,and her2-neu-gene negative. what this implies is that hormone therapiessuch as aromatase inhibitors or tamoxifen would have no effect in the treatment of thatcancer and herceptin, which is used in her2 positive breast cancers also would not beeffective.
triple negative breast cancer treatment, so that what we are left with is chemotherapy.there have been a number of attempts to find specific chemotherapies that may work betterin triple negative breast cancer. there is some hint that platinum drugs such as carboplatinor cisplatin may be more effective in triple negative breast cancer and there are now severalclinical trials looking at platinum-based
therapies versus more conventional chemotherapieswith adriamycin and cytoxan and a taxane to see if indeed the platinum drugs are moreeffective. there are also studies looking at avastin,which is an anti-angiogenesis drug to see if it may be more effective in triple negativebreast cancer and also trials looking at a group of drugs called parp inhibitors thatare specific to triple negative breast cancers and there was some initial data that theydid work quite well in triple negative breast cancers but at least the first drug trialwhen expanded to more patients was somewhat disappointing. there are, however, a number of clinical trialslooking at other parp inhibitors and obviously
we hoped that they panned out as being bettertreatments for triple negative breast cancer. triple negative breast cancer because chemotherapyis the only avenue of treatment, can be quite frustrating because the patient may be onchemotherapy for prolonged periods of time and beyond that triple negative breast cancerstend to be one of the more aggressive forms of breast cancer. ***** hi, i am dr. jay harness and i want to sharewith you an important information that i believe that every newly diagnosed patient with breastcancer needs to know. susan denver: “i am a breast cancer survivor.â€
katherine stockton: “i am a breast cancersurvivor.†coree: “i am a breast cancer survivor…†susan denver: “…and i want every womanto know…†katherine stockton: “…about personalizedbreast cancer treatment…†susan denver: “…and the genomic test.†coree: “a test that helps guide a womanand her doctor…†katherine stockton: “…to the best treatmentoptions for her.†susan denver: “pass it on!â€
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